Cost of Goods Modeling

Bioprocess Technology Consultants has extensive experience building process and economic models to evaluate manufacturing options and process details. We can estimate operational and capital costs for manufacturing facilities aiding in make versus buy decisions. Using these tools we can assist you in critically evaluating your development or manufacturing program, estimating validation costs or assessing process economic feasibility. Our modeling expertise can also help you evaluate the impact of new technologies or process changes on overall manufacturing costs and facility utilization.

We can develop process and cost models for the evaluation of both commercial and clinical production based on a variety of manufacturing technologies, including mammalian cell culture, microbial fermentation, insect cell culture, and transgenic plants and animals. Our broad experience and capabilities include the construction of process and cost models for recombinant proteins, monoclonal antibodies, vaccines, synthetic peptides, and industrial processes. These models can be built using either our proprietary in-house Microsoft Excel® based models or using commercially available modeling software from BioPharm Services (BioSolve) or Intelligen (SuperPro Designer® and SchedulePro®). Since these commercial products require licenses for use, we have established working relationships with both vendors to allow for a seamless transition to our clients who wish to continue to license these products after completing a project. The choice of modeling software used for your project will depend on the details of your process and the specific requirements of your project. Using these various modeling options, we can quickly and easily assist you with such information as:

  • Estimating the total size and cost of constructing new manufacturing facilities or renovating existing facilities
  • Assessing the relative costs and tradeoffs of single use versus fixed reusable technologies for production
  • Analysis of the direct and indirect labor requirements and costs for any manufacturing process or operational scenario